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Nolph and Gokal’’s Textbook of Peritoneal Dialysis

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Nolph and Gokal’s Text Book of Peritoneal Dialysis, Third Edition, covers advances made in the field for the past 30 years. During the past two decades, the time during which this therapy has been increasingly utilized, this text has continued to be recognized as the major source of the disciplin

e’s base knowledge. The evolution of this text to its newest edition parallels the growth of peritoneal dialysis from Continuous Ambulatory Peritoneal Dialysis in the eighties to the current therapy that encompasses manual and automated therapies with full emphasis on adequacy of dialysis dose.Perit

oneal dialysis represents an intracorporeal technique for blood purification. This unique dialysis system represents one of many human attempts to manipulate nature for sustenance of life. The past few years of advances have focused on further improvement of the technique. Areas that have fueled the

interest of researchers include: (1) Physiology of high transporters (and the role of genetics and inflammation); (2) Continued debate over the most appropriate adequacy indices (small solute clearances, large solute clearances, clinical assessment etc.); (3) Understanding, preventing and treating

the MIA syndrome in PD patients ( including the roles of leptin, and adiponectin); (4) Pathogenesis and newer management strategies of vascular calcification; (5) Continued improvements in infectious complications including peritonitis; (6) Further improvements in catheter technology; (7) Automated

techniques; (8) Explaining and correcting PD underutilization; (9) Rationale and applications of newer dialysis solutions; (10) New understanding and approaches to management of osteodystrophy; (11) Refinements in anemia management including new insights in iron metabolism in PD patients; (12) Furth

er definition of indications for PD; (13) The ideal time to initiate dialysis.Newer insight into host defense mechanisms have also made the past decade of advances in the field more meaningful for clinicians. This text also covers the knowledge gained from animal models of peritoneal dialysis.Nolph

and Gokal’s Textbook of Peritoneal Dialysis, Third Edition is a compilation of the latest knowledge in the field. It cites and describes in great detail, the new discoveries and the evolution of understanding the subject of these discoveries.

Checkmate: A True Story

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Randy Holcomb is the former Chicago PD Detective depicted in the novel who was friends with Rico. He worked with Grant as she wrote Checkmate. AnnaLisa Grant is the bestselling author of The Lake Series, which ranked #1 on Amazon for several consecutive months and has over 1 million copies in circul

ation. The Lake is currently in development for a TV series. Nick Fullen-Collins discovered the screenplay for Checkmate and bought the rights to develop, produce, and novelize. During his career, he has worked for the President and CEO of Queen Latifah’s Flavor Unit Entertainment as well as on the

critically acclaimed, Emmy Award-winning HBO film, Bessie, starring Queen Latifah. Most recently, Nick was at HBO in various departments, including Drama, in which he worked for the vice president who oversaw, Game of Thrones. He also helped manage and coordinate the 2016 HBO Access writers and dire

ctors’ program in the Talent/Development department.

可攜式腦波檢測入眠裝置之研製與以其發展音樂助眠系統之研究

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失眠是現今高壓且快速社會中人們困擾的問題，無法放鬆入睡失眠，或定義為開始入睡困難，是一種常見的疾病，造成人們無法快速進入睡眠。本研究研製了一種藉偵測腦波狀態以判斷入睡時間點以開關助眠音樂，以期幫助有失眠困擾的人容易入眠。研究分成四個階段進行，其第一階段先在Linux環境樹莓派中撰寫Python程式，改裝Neurosky腦波儀，使其不受限於Windows環境，發展一個可攜型的睡眠腦波偵測儀。第二階段即立基於所發展的睡眠腦波偵測儀，參考文獻設計出一套基於單一FP1頻道之δ波上升以及α 波下降判斷人體何時入眠之檢測演算法，並撰寫程式於樹莓派中。第三階段再以一所發展的軟、硬體核心配合一音樂播放裝置，

整合為一睡前即播放助眠音樂，直到偵測得入眠時間，加上一略為滯後的延遲即淡出關閉音樂之助眠裝置，反覆驗證所發展的軟、硬體，直到信賴可實際應用。第四階段再以發展完成的裝置循正規之睡眠測驗進行其性能測試，在9名受試者共27天配戴中，與市售智能裝置的夜間睡眠資料進行比對，其在辨認入睡時間具有一定之一致性，差異度僅為11%。另外在26名依匹茲堡睡眠品質表所得之PSQI指數分為好(0-5)與不好(6-12)兩組的受試者中，分別分析所研製裝置對於兩個群組睡眠品質造成的影響，根據兩群組受試者各自6天共156天的睡眠資料調查結果表明: 對於睡眠品質好的人連續使用可以減少其入睡時間，第三天時比起平常減少1.42分

鐘。但對於睡眠品質差的人反而會造成其睡眠時間延長，第三天時比起平常延長1.71分鐘，本研究的新穎處在於研製了一種準確度不亞於市售穿戴裝置且成本遠低於醫院PSG設備的可攜式腦波入睡偵測裝置，其整合音樂播放的延伸的助眠裝置可以使得睡眠品質好的人有效減少其入眠時間，提升睡眠品質。